Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Apical-like protein (actin filament binding)

Seq-ID:

A2ALU4 [Mus musculus]

Download:

Interaction Network(s):

-

External Source(s):

Phosida

Phosida

MINT Interaction(s):

-

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein domain specific binding, beta-catenin binding, actin filament binding	cell-cell adherens junction, neuronal cell body, apical plasma membrane, microtubule, tight junction	brain development, cellular pigment accumulation, establishment of melanosome localization, melanosome organization, cell migration, negative regulation of actin filament depolymerization, cell-cell junction maintenance, eye pigment granule organization, apical protein localization, lens morphogenesis in camera-type eye, ear development

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	933	KPLEARSSGRYHSADDILDAG	-	17242355	HTP	1.00		-	-	0.69	-	medium
S	960	PQYIHERSRSSPSTDHYSQEV	-	17242355	HTP	1.00		-	-	0.80	-	medium
S	1165	PAPPVRDSCSSPPSLNYGKAK	-	17242355	HTP	1.00		-	-	0.74	-	medium
S	1165	PAPPVRDSCSSPPSLNYGKAK	-	17114649	HTP	1.00		-	-	0.74	-	medium

Apical-like protein (actin filament binding)

Seq-ID:

Q13796 [Homo sapiens]

Download:

Interaction Network(s):

STRING

External Source(s):

Phosida

Phosida

MINT Interaction(s):

[show]

MINT-7245346   SRC_HUMAN
MINT-7247050   FYN_HUMAN
MINT-7250302   NCK1_HUMAN
MINT-7253590   GRB2_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
amiloride-sensitive sodium channel activity, beta-catenin binding, actin filament binding	cell-cell adherens junction, apical plasma membrane, microtubule, tight junction	brain development, cellular pigment accumulation, establishment of melanosome localization, melanosome organization, cell migration, eye pigment granule organization, apical protein localization, lens morphogenesis in camera-type eye, ear development

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	366	QPRGDRRPELTDRPWRSAHPG	-	17081983	HTP	0.04		-	-	0.92	-	medium
S	1443	LSVKKQELIESISRKLQVLRE	-	17081983	HTP	1.00		-	ASD2	0.31	-	medium